When two bones repeatedly rub together, it will usually cause the outer coating of a nerve in a foot to swell.  This swelling is called a neuroma or a Morton's neuroma. It is most commonly occurs between the third and fourth toe.

The pain from the neuroma may start gradually and become more severe over time. It is described as a burning, cramping, or aching sensation, but may also cause tingling or numbness. It usually occurs after walking or standing on your feet for a long period of time and is commonly found in people who wear tight-fitting shoes. Perhaps, unsurprisingly, almost 90% of all Neuroma's are found in females between the ages of 18 - 85 year old.